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NICU Staphylococcus aureus

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Surveillance Cultures ➤ No specific standard protocol exists for frequency of S. aureus surveillance testing, specific population(s) to test, or duration of active surveillance. ➤ For MRSA • Consider routine active surveillance when the results can inform: ▶ Infection prevention and control measures (e.g., patient cohorting, contact precautions, and/or decolonization), and/or ▶ Clinical management decisions (i.e., antibiotic selection if subsequent invasive disease occurs). • In specific situations, perform active surveillance to inform additional infection prevention strategies when: a. an outbreak has been identified; b. healthcare-associated transmission is ongoing and of clinical importance; or c. an individual patient may be at higher risk for colonization or infection (e.g., prior to surgery, multiple gestation with differing MRSA colonization status, parent known to be a carrier or otherwise infected with MRSA, or outborn newborns from settings of higher prevalence). ➤ For MSSA • Routine active surveillance has no clear benefit unless results inform infection prevention and control measures (e.g., decolonization). • In specific situations, consider performing active surveillance to inform additional infection prevention strategies when: 1. an outbreak has been identified, and 2. when there is a need to identify individual patients who may be at higher risk for infection (e.g., low birth weight or prior to surgery). ➤ Do NOT routinely perform S. aureus testing of equipment and/or other environmental surfaces. ➤ Units: • Should use culture-based or molecular methods for S. aureus surveillance, with anterior nares being the preferred site to sample. If multiple sites are sampled, consider performing a composite culture of all swabs. ➤ Units: • Should institute contact precautions for infants with positive MRSA test results. Interventions

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