Healthy Adults
Recommendation 12
➤ In healthy adults, we suggest against routine screening for 25(OH)D levels.
(2|⊕
)
Technical remarks:
• In healthy adults, 25(OH)D levels that provide outcome-specific benefits have not been
established in clinical trials.
• This recommendation relates to adults who do not otherwise have established indications
for testing with 25(OH)D levels (e.g., hypocalcemia).
Adults with Dark Complexion
Recommendation 13
➤ In adults with dark complexion, we suggest against routine screening for
25(OH)D levels. (2|⊕
)
Technical remarks:
• This recommendation relates to generally healthy adults with dark complexion who do
not otherwise have established indications for 25(OH)D testing (e.g., hypocalcemia).
• The panel did not identify any clinical trials that related clinical outcomes to skin
complexion per se. A secondary analysis did not clearly suggest net benefit with vitamin
D in those who self-identify as Black. The panel recognized that self-identified race is an
inaccurate and otherwise problematic proxy for dark complexion.
Adults with Obesity
Recommendation 14
➤ In adults with obesity, we suggest against routine screening for 25(OH)D
levels. (2|⊕
)
Technical remarks:
• In adults with obesity, 25(OH)D thresholds that provide outcome-specific benefits have
not been established in clinical trials
• This recommendation relates to generally healthy adults with obesity who do not
otherwise have established indications for 25(OH)D testing (e.g., hypocalcemia).
Treatment
