Nonpregnant Adults <50 Years of Age
Recommendation 2
➤ In the general adult population younger than age 50 years, we suggest against
empiric vitamin D supplementation. (2|
⊕
)
Technical remark:
• This recommendation relates to empiric vitamin D supplementation that exceeds the
Dietary Reference Intakes (DRIs) established by the Institute of Medicine (IOM). Adults
in this age group should follow the Recommended Daily Allowance established by the IOM
(600 IU [15 μg ] daily).
Recommendation 3
➤ In the general adult population younger than age 50 years, we suggest against
routine 25(OH)D testing. (2|
⊕
)
Technical remarks:
• In this population, 25(OH)D levels that provide outcome-specific benefits have not been
established in clinical trials.
• The panel suggests against (a) routine screening for a 25(OH)D level to guide decision-
making (i.e., vitamin D vs no vitamin D) and (b) routine follow-up testing for 25(OH)D
level to guide vitamin D dosing.
• This recommendation relates to generally healthy adults who do not otherwise have
established indications for 25(OH)D testing (e.g., hypocalcemia).
Adults Aged 50–74 Years
Recommendation 4
➤ In the general population ages 50 to 74 years, we suggest against routine
vitamin D supplementation. (2|⊕⊕⊕)
Technical remark:
• This recommendation relates to empiric vitamin D supplementation that exceeds the DRIs
established by the IOM. Adults in this age group should follow the Recommended Daily
Allowance established by the IOM (600 IU [15 μg] daily for those aged 50 to 70 years;
800 IU [20 μg] daily for those older than 70 years).
Recommendation 5
➤ In the general population ages 50 to 74 years, we suggest against routine
25(OH)D testing. (2|
⊕
)
Technical remarks:
• In this population, 25(OH)D levels that provide outcome-specific benefits have not been
established in clinical trials.
• The panel suggests against (a) routine screening for a 25(OH)D level to guide decision-
making (i.e., vitamin D vs no vitamin D) and (b) routine follow-up testing for 25(OH)D
level to guide vitamin D dosing.
• This recommendation relates to generally healthy adults who do not otherwise have
established indications for 25(OH)D testing (e.g., hypocalcemia).
Treatment
