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Glucocorticoid-Induced Adrenal Insufficiency

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10 Tables Table 1. Pharmacologic Characteristics of Commonly Prescribed Systemic Glucocorticoids Glucocorticoids Approximate equivalent dose 1 Glucocorticoid potency (relative to hydrocortisone) 1,2 Short-acting glucocorticoids with lower potency Hydrocortisone 20 mg 1.0 Cortisone acetate 25 mg 0.8 Deflazacort 7.5 mg 1.0 Intermediate-acting glucocorticoids with moderate potency Prednisone 5 mg 4.0 Prednisolone 5 mg 4.0 Triamcinolone 4 mg 5.0 Methylprednisolone 4 mg 5.0 Long-acting glucocorticoids with highest potency Dexamethasone 0.5 mg 30–60 Betamethasone 0.5 mg 25–40 1 ese are estimates based on historically accepted conversion factors and should be seen as a guide only. ere can be considerable variation depending on factors such as route of administration, the individual patient's metabolism and susceptibility. 2 Glucocorticoid potency equivalences apply to oral and/or intravenous administration. Mineralocorticoid effects are not considered. 3 Plasma half-life does not reflect the biological half-life.

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