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Lower Extremity Peripheral Artery Disease 2024

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11 Table 5. Patients at Increased Risk for PAD Age ≥65 y Age 50–64 y, with risk factors for atherosclerosis (eg, diabetes, history of smoking, dyslipidemia, hypertension), chronic kidney disease, or family history of PAD Age <50 y, with diabetes and 1 additional risk factor for atherosclerosis Individuals with known atherosclerotic disease in another vascular bed (eg, coronary, carotid, subclavian, renal, mesenteric artery stenosis, or AAA) Modified with permission from Gerhard-Herman MD, et al. Copyright © 2017 American Heart Association, Inc., and American College of Cardiolog y Foundation. Table 6. History and Physical Examination Findings Suggestive of PAD History • Claudication ▶ Pain type: Aching, burning, cramping, discomfort, or fatigue ▶ Location: Buttock, thigh, calf, or ankle ▶ Onset/offset: Distance, exercise, uphill, how long for relief after rest (typically <10 min for typical claudication) • Other nonjoint-related exertional lower extremity symptoms (not typical of claudication) or symptoms of impaired walking function ▶ Lower extremity muscular discomfort associated with walking that requires >10 min rest to resolve ▶ Leg weakness, numbness, or fatigue during walking without pain • Ischemic rest pain • History of nonhealing or slow-healing lower extremity wound • Erectile dysfunction Physical Examination • Abnormal lower extremity pulse palpation (femoral, popliteal, dorsalis pedis, or posterior tibial arteries) • Vascular bruit (eg, epigastric, periumbilical, groin) • Nonhealing lower extremity wound • Lower extremity gangrene • Other physical findings suggestive of ischemia (eg, asymmetric hair growth, nail bed changes, calf muscle atrophy, or elevation pallor/dependent rubor) Modified with permission from Gerhard-Herman MD, et al. Copyright © 2017 American Heart Association, Inc., and American College of Cardiolog y Foundation.

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