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Thyroid Hormones

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2 Key Points ➤ The "quality" of thyroid testing is defined by its ability to discriminate among hyperthyroid, hypothyroid and euthyroid, including subclinical conditions. ➤ Over the past 65 years, a progressive improvement in methods to quantitate clinically relevant thyrotropin (TSH), thyroxine (T4), and triiodothyronine (T3) concentrations has led to this state-of-the-art status report on current recommendations. ➤ Because of the log-linear relationship of TSH to free T4 (fT4), deviations of TSH concentration from population-specific reference intervals represent the preferred initial test for evaluation of thyroid function.

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