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Depression 36 Table 3. Commonly Used Antidepressant Dosing Generic Name Average Starting Dose (mg/day) Average Target Dose after 6 weeks (mg/day) Maximum Recommended Dose for Older Adults (mg/day) Citalopram 10 10–20 20 Escitalopram 5 5–10 10 Sertraline 25 50–150 200 Duloxetine 20 30–60 60 Venlafaxine ER 37.5 75–150 225 (375 for severe depression) Mirtazepine 7.5–15 15–30 45 Buproprion 75–100 BID 100 BID–TID 150 BID Buproprion ER 150 150 BID 300 BID
