AMDA Pocket Guidelines

Dementia Depression Delirium

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31 STEP 5: Determine type of depressive disorder Types of Depression ➤ Major Depressive Disorder (MDD): Symptoms are experienced most days and last for at least two weeks. ➤ Dysthymia: Symptoms of dysthymia are similar to MDD but are less severe and last longer – at least two years. ➤ Bipolar disorder: Periods of depression and periods of mania with normal mood in between. ➤ Melancholic depression: Severe form of depression characterized by a near-complete absence of the capacity for pleasure, psychomotor agitation or retardation, neurocognitive impairment, significant weight loss or anorexia, interrupted sleep, and a diurnal variation (mood and energy worse in the morning). Types of Grief ➤ Grief: Grief after the death of a loved one is a normal reaction to loss and generally does not require treatment. ➤ Complicated grief: Lasts a very long time (6-12 months) or/and is severe and may require treatment. STEP 4: Perform a medical evaluation ➤ When evaluating depression in older adults, consider checking blood count, glucose level, thyroid-stimulating hormone and vitamin B12/ folate. 16 ➤ Cognitive assessment should be included in evaluation since depression in older adults is also associated with cognitive impairment. Refer to Table 7 in Dementia section. ➤ Evaluate for common medications which can induce or worsen depressive symptoms or cause depression itself. 19 ➤ Evaluate for substance use (i.e., alcohol, illicit drugs). • Anti-arrythmic medications • Anticonvulsants • Barbiturates • Benzodiazepines • Bromocriptine • Calcium-channel blockers • Carbidopa-levodopa • Certain beta-adrenergic blockers (e.g. propranolol) • Clonidine • Cytokines / Interferon alfa • Digoxin • Fluoroquinolone antibiotics • Opioids

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