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Dyslipidemia-II NLA

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27 Chart 10. African Americans (AAs) Recommendations Strength Quality In general, AAs should be treated according to the NLA Recommendations for Patient-Centered Management of Dyslipidemia – Part 1 with the following special considerations. A High Clinicians should be aware that AAs as a group are at increased risk for ASCVD. A High Because attributable ASCVD risk in AAs is less driven by dyslipidemia than in NHWs, particular attention should be given to assessing non-lipid risk factors, such as hypertension, overweight and obesity, type 2 diabetes mellitus, and physical inactivity, when ascertaining ASCVD risk. A High AAs have a lower incidence of metabolic syndrome than NHWs, due to lower prevalence of high TG and low HDL-C. However, the incidence of type 2 diabetes mellitus is higher in AAs. A High Because AA race/ethnicity is included in the 2013 ACC/ AHA Pooled Cohort Equations for estimating 10-year ASCVD risk, this may be the preferable risk calculator to use in patients of AA race/ethnicity. B Moderate Because Lp(a) levels tend to be higher in AA patients, measuring Lp(a) for risk refinement may be considered in AA patients, particularly in those with a family history of premature ASCVD not explained by other risk factors. E Moderate Clinicians should not withhold statin therapy from at risk AA patients with asymptomatic creatine kinase levels that exceed, but are <3.0 times, the standard upper limits of normal. When practical, normative upper limits for creatine kinase that are adjusted for age, race, and sex should be used. E Moderate

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