7
Cost
Benefit-Harm
Assessment Policy Level
Low to
Moderate
Benefit over placebo
is small
Option: Consider watchful waiting in
uncomplicated cases with institution
aer 7 days or with worsening/mitigating
circumstances
None Benefits likely outweigh
harms and costs
Recommendation: Antibiotics should
not be given for the first 10 days of
uncomplicated pediatric ARS. If >10 days
or complicated, amoxicillin-clavulanate is
preferred antibiotic if not allergic
Low Benefit over placebo
small but tangible
Strong Recommendation: Consider use
in ARS
Low Balance of benefit
and harm
Option: Saline irrigation may be used in
adjunct with antibiotics for acute bacterial
rhinosinusitis
