4
Treatment
Table 2. Classes of Interventions
Nonsteroidal anti-inflammatory
drugs (NSAIDs)
Any at therapeutic dosing (Ibuprofen,
Naproxen, Tolmetin, Indomethacin, Meloxicam,
Nabumetone, Diclofenac, Piroxicam, Etodolac,
Celecoxib)
Conventional synthetic disease-
modifying antirheumatic drugs
(DMARDs)
Methotrexate (MTX), Sulfasalazine (SSZ),
Hydroxychloroquine (HCQ), Leflunomide
(LEF), Calcineurin inhibitors (cyclosporin A,
tacrolimus)
Biologic disease-modifying
antirheumatic drugs (DMARDs)
• Tumor necrosis factor alpha inhibitors
(TNFi): Adalimumab, Etanercept, Infliximab,
Golimumab, Certolizumab pegol
• Other biologic response modifiers (OBRM):
Abatacept, Tocilizumab, Anakinra,
Canakinumab
Glucocorticoids (GC) • Oral: Any
• Intravenous: Any
• Intra-articular: Triamcinolone Acetonide,
Triamcinolone Hexacetonide
