Treatment
Table 2. Recommendations for the pharmacologic management
of osteoarthritis of the hand, knee, and hip
Intervention
Joint
Hand Knee Hip
Topical nonsteroidal
antiinflammatory drugs
Topical capsaicin
Oral nonsteroidal antiinflammatory
drugs
Intraarticular glucocorticoid injection
Ultrasound-guided intraarticular
glucocorticoid injection
Intraarticular glucocorticoid injection
compared to other injections
Acetaminophen
Duloxetine
Tramadol
Non-tramadol opioids
Colchicine
Fish oil
Vitamin D
Bisphosphonates
Glucosamine
Chondroitin sulfate
Hydroxychloroquine
Methotrexate
Intraarticular hyaluronic acid injection (First
carpometacarpal)
Intraarticular botulinum toxin
Prolotherapy
Platelet-rich plasma
Stem cell injection
Biologics (tumor necrosis factor
inhibitors, interleukin-1 receptor
antagonists)
