50
Special Populations
Table 18. Traditional and Nontraditional Risk Factors
Associated With CCD in Young Adults
Traditional Risk Factors Nontraditional Risk Factors
Hypertension (See Section 4.2.7,
"Blood Pressure Management")
HIV and ART (See Section 6.8, "HIV/
Autoimmune Disorders")
Obesity and metabolic syndrome
(See Section 4.2.9, "Weight
Management")
Recreational substance use (cocaine and
marijuana) (See Section 4.2.4, "Alcohol and
Substance Use")
Diabetes (See Section 4.2.8, "Sodium
Glucose Cotransporter 2 Inhibitors
and Glucagon Peptide-1 Receptor
Agonists")
Systemic inflammatory disorders (IBD, SLE,
RA, gout, PsA, AS) and vasculitides
Unhealthy diet and physical inactivity
(See Section 4.2.1, "Nutrition,
including Supplements," and Section
4.2.11, physical activity)
Pregnancy-related complications (IUGR,
HDP, gestational diabetes) (See Section 6.5,
"Women, Including Pregnancy and Hormone
Therapy")
Hyperlipidemia (LDL-C, Lp(a)) (See
Section 4.2.6, "Lipid Management")
Familial hypercholesterolemia
Tobacco use (See Section 4.2.3,
"Tobacco Products")
Miscellaneous (psychological well-being, sleep
quality, social determinants of health (See
Section 4.1.4, "Social Determinants of Health,"
and Section 4.2.2, "Mental Health")
Family history of premature CAD History of chest radiation
Adapted from Mahtta D, et al. Curr Atheroscler Rep. 2020;22:44. by permission from Springer
Nature, Copyright 2020.
