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Table 14. Screening Questions for SCAD-Associated
Arteriopathies and Connective Tissue Disorders
Personal history (Have you ever been diagnosed with or experienced any of the
following?)
• Early-onset hypertension
• Stroke or transient ischemic attack
• Pulsatile tinnitus
• Migraine headaches
• Renal infarction
• Subarachnoid hemorrhage
• Aneurysm (aortic, peripheral, brain)
• Dissection (aortic, peripheral)
• Rupture of hollow organs (intestinal, bladder, uterine)
• Pneumothorax
• Tendon or muscle rupture
• Joint dislocation
• Talipes equinovarus (clubfoot)
• Umbilical or inguinal hernia
• Scoliosis or pectus deformity
• Pregnancy complications (cervical incompetence, hemorrhage, uterine prolapse,
hypertension)
• Poor wound healing
• Ectopia lentis
• Myopia
• Detached retina, early glaucoma, or early cataracts
• Tall stature
• Abnormality of cardiac valve
• Systemic inflammatory disease
Family history (Does anyone in your family have the following?)
• Dissection (coronary, aortic, peripheral)
• Inherited arteriopathy or connective tissue disorder (eg, vascular Ehlers-Danlos
syndrome, Marfan syndrome, Loeys-Dietz syndrome)
• Early stroke, early myocardial infarction, sudden cardiac death
Review of systems (Are you currently experiencing any of the following?)
• Headaches
• Pulsatile tinnitus
• Postprandial abdominal pain
• Flank pain
• Claudication
• Easy bruising
• Joint hypermobility or laxity
Reprinted with permission from Hayes SN, et al. Am J Cardiol. 2015;115:1672-1677.
Copyright 2007 American Heart Association, Inc.
