6
Table 2. Recessive forms (type 2) of LGMDs associated with
CM, listed according to the subtype nomenclature
used in this guide
New classification system in parentheses
Subtype (prior name) Gene Protein
Cellular
localization
LGMD2D (LGMD R3) SGCA α-Sarcoglycan Sarcolemma
LGMD2E (LGMD R4) SGCB β-Sarcoglycan Sarcolemma
LGMD2C (LGMD R5) SGCG γ-Sarcoglycan Sarcolemma
LGMD2F (LGMD R6) SGCD δ-Sarcoglycan Sarcolemma
LGMD2G (LGMD R7) TCAP Telethonin Sarcomere
LGMD2I (LGMD R9) FKRP Fukutin-related protein Golgi apparatus
LGMD2J (LGMD R10) TTN Titin Sarcomere
LGMD2N (LGMD R14) POMT2 Protein
O-mannosyltransferase 2
Endoplasmic
reticulum
LGMD2Q (LGMD R17) PLEC Plectin Intermediate filament
Duchenne, Becker, and Recessive Limb-girdle
Muscular Dystrophies
