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Evaluation and Management of Arrhythmic Risk in Neuromuscular Disorders

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15 Management strategies Key points • Management options discussed included observation, loop recorder insertion, and pacemaker implantation (leadless, transvenous single-chamber versus dual- chamber). • Values elicited in discussion included desire to avoid recurrent syncope and injury, simplicity of treatment, and preference for quick recovery. • Leadless pacemaker was chosen by the patient to provide protection against arrhythmia recurrence and the most likely cause of syncope and associated injury. • Relatively simple procedures (pacemaker implantation) may be associated with a higher rate of complications or prolonged recovery in this and similar populations. • Dual-chamber pacemaker implantation with atrial lead implantation for underlying sinus node dysfunction is unlikely to provide significant additional benefit but may be accompanied by a higher frequency of procedural risks and prolonged recovery (such as infectious and respiratory complications, including pneumothorax). • Therapies targeting quality of life remain the primary focus in patients with advanced neuromuscular involvement.

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