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Cardiac Physiologic Pacing for the Avoidance and Mitigation of Heart Failure

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35 ECG considerations Major complications • The onset of QRS to LV time <90 ms • Lead I: non-QS or QR • Intrinsic QRS duration <120 ms or narrower than optimized pace QRS duration • Pericardial effusion/Tamponade • CS or vascular dissection • Cardiac arrest • Sustained ventricular tachyarrhythmia • Others (PE, stroke, respiratory failure, etc.) • For baseline wide QRS, unable to have paced QRS duration ≤130 ms or QRS narrowing >20% • Unable to achieve selective or nonselective His capture • Same as in CRT with BiV pacing • Lead dislodgement • Reduced battery longevity due to elevated pacing capture thresholds • Late rise in thresholds • Unable to achieve the RBBB configuration or to have paced QRS duration ≤130 ms • Unable to achieve LVAT <74–80 ms • Same as in CRT with BiV pacing • Risk of late septal perforation

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