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Cardiac Physiologic Pacing for the Avoidance and Mitigation of Heart Failure

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18 Indications for CPP in Atrial Fibrillation (AF) CPP in AF COR LOE Recommendations 2a B-R 1. In patients with AF undergoing atrioventricular junction (AVJ) ablation with LVEF ≤50%, CRT with BiV pacing is reasonable to improve HFH, reverse structural remodeling, and improve quality of life, exercise capacity, LVEF, and potentially mortality. 2a B-NR 2. In patients with AF who otherwise meet CRT implantation eligibility criteria, CRT with BiV pacing can be beneficial to improve quality of life, functional capacity, and LVEF. 2b C-LD 3. In patients with AF undergoing AVJ ablation, HBP with or without a backup ventricular pacing lead may be reasonable to improve or preserve LVEF and improve functional class. 2b C-LD 4. In patients undergoing AVJ ablation, it may be reasonable to implant an LBBAP lead. 2b C-LD 5. In patients with a high burden of ventricular pacing, HBP or LBBAP may be reasonable to decrease the risk of AF.

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