83
Table 35. Diagnostic Criteria for Inflammatory Aortitis
Names Criteria Used in Diagnosis/Source
When Is Diagnosis
Established?
Takayasu
arteritis
Age of onset <40 y ≥3 criteria are
present
(sensitivity 90.5%;
specificity 97.8%)
Intermittent claudication
Diminished brachial artery pulse
Subclavian artery or aortic bruit
Systolic BP variation of >10 mm Hg between arms
Aortographic evidence of aorta or aortic branch
stenosis
Giant cell
arteritis
Age >50 y ≥3 criteria are
present
(sensitivity >90%;
specificity >90%)
Recent-onset localized headache
Temporal artery tenderness or pulse attenuation
Elevated erythrocyte sedimentation rate >50 mm/h
Arterial biopsy shows necrotizing vasculitis
Originally published in Hiratzka, et al. 2019. Circulation. 2010;121:e266-e369.
9.2.1. Diagnosis and Management of Infection of the Native
Aorta
COR LOE
Recommendations
1 C-EO 1. In patients with infectious aortitis and associated aneurysms
or dissection of the thoracic or abdominal aorta, open surgical
repair is recommended.
2b C-LD In select patients, treatment with endovascular repair may be
considered.
2a C-EO 2. In patients with infectious aortitis complicated by rupture,
either open or endovascular repair is reasonable, based on the
patient's status at presentation and institutional expertise.
2b C-EO 3. In patients with infectious aortitis, intravenous antimicrobial
therapy of at least 6 weeks' duration may be considered, with
lifelong suppressive therapy in select cases not amenable to
interventional repair or who have recurrent infection.
