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Diagnosis and Management of Aortic Disease

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51 6.5.3.2. Endovascular Versus Open Repair of Descending TAA COR LOE Recommendations 1 B-NR 1. In patients without Marfan syndrome, Loeys-Dietz syndrome, or vascular Ehlers-Danlos syndrome, who have a descending TAA that meets criteria for intervention and anatomy suitable for endovascular repair, TEVAR is recommended over open surgery. 1 B-NR 2. In patients with a descending TAA that meets criteria for repair with TEVAR, who have smaller or diseased access vessels, considerations for alternative vascular access are recommended. 2a B-NR 3. In patients with a descending TAA that meets criteria for intervention, who have anatomy unsuitable for endovascular repair, and who are without significant comorbidities and have a life expectancy of at least 10 years, open surgical repair is reasonable. Table 18. Patient Characteristics Associated With Increased Perioperative Morbidity and Mortality After Open and Endovascular Repair of Descending TAA Open Surgical Repair Endovascular Repair Advanced age 65–74 y (OR, 1.8; 95% CI, 1.4–2.4; P<0.001) ≥75 y (OR, 2.6; 95% CI, 2.0–3.5; P<0.001) Functional dependence Preoperative renal insufficiency (stage 3 or greater CKD) or hemodialysis oracoabdominal aortic aneurysm extent COPD and FEV1 ≤50% predicted Pulmonary disease Previous stroke Need for iliac access Zone 1/2 landing for thoracic stent gra

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