10
Treatment
Table 2. Summary of Recommendations for Treatment of PsA
in the Case of Comorbidities
Comorbidity NSAIDs GCs MTX and/or LEF
Elevated risk of cardiovascular
disease (CVD)
Caution — —
Congestive heart failure
a
— Caution —
Elevated risk for venous
thromboembolism (VTE)
— — —
Obesity — — Caution
Fatty liver disease — — Avoid
Active hepatitis B or C — — Avoid
HIV — — —
Tuberculosis — — —
History of recent malignancy — — —
Multiple sclerosis (MS) and/or
demyelinating disease
— — —
Depression and/or anxiety — — —
a
Severe or advanced; class III or IV according to the New York Heart Association (NYHA)
Functional Classification.
