9
Go to Figure 2
Refer to appropriate
ASCO guideline for
specific primary site
Random biopsies of non suspicious
areas should not be performed
• Complete operative upper aerodigestive
tract evaluation of mucosal sites at-risk
(oral cavity, nasapharynx, oropharynx,
hypopharynx, and larynx), including
directed biopsy of any suspicious areas.
• Narrow-band imaging may be helpful
Unilateral
lymphadenopathy
Primary identified
No primary identified
Bilateral
lymphadenopathy
Ipsilateral palatine
tonsillectomy
Unilateral lingual
tonsillectomy on the
side with the greater
nodal burden
e
Ipsilateral lingual
tonsillectomy
c,e
Contralateral lingual
tonsillectomy
d,e
No primary
identified— i.e.,
SCCUP
Ipsilateral palatine
tonsillectomy on the
side with greater nodal
disease
e
No primary identified
No primary identified
No primary identified
