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Noncastrate Advanced, Recurrent or Metastatic Prostate Cancer Initial Management

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Figure 1. Patients with Noncastrate Recurrent, Advanced, or Metastatic Prostate Cancer Biochemical recurrence after RP and/or RT only* Locally advanced Unwilling or unable to undergo RT Early ADT Active surveillance Low risk Undergoing RT ADT + abiraterone + predisnone/ prednisolone Intermittent ADT High risk * Consult Lowrance WT et al, 2020 1 (American Urological Association/American Society for Radiation Oncolog y/Society of Urologic Oncolog y Advanced Prostate Cancer: AUA/ ASTRO/SUO Guideline PART I) and Bekelman JE, 2018 2 (ASCO clinical practice guideline endorsement of an American Urological Association/American Society for Radiation Oncolog y/ Society of Urologic Oncolog y guideline) for further information regarding salvage therapy options aer failure of local therapy. 1 Lowrance WT, Breau RH, Chou R, Chapin BF, Crispino T, Dreicer R, Jarrard DF, Kibel AS, Morgan TM, Morgans AK, Oh WK. Advanced Prostate Cancer: AUA/ASTRO/SUO Guideline PART I. e Journal of Urolog y. doi:10.1097/JU.0000000000001375

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