6
Treatment
Table 2. Proposed Terms to Characterize ONJ After
Treatment
Mucosal
coverage
Symptoms/
pain
Signs of
infection/
inflammation Radiographic
Resolved Complete
healing
No pain None Trabecular
pattern,
formation
lamina dura
resorbed
Improving Significant
improvement
(>50% of
mucosal
coverage)
Significant
improvement
(>50%
reduction of
pain – VAS)
Significant
improvement
(no signs of
infection/
inflammation)
Improved
trabecular
pattern
Signs of
sequestra
Stable Mild
improvement
(<50% of
mucosal
coverage)
Mild
improvement
(<50%
reduction of
pain – VAS)
Mild
improvement
(mild signs
of infection/
inflammation)
No changes
Progressive No
improvement or
worsening
No
improvement or
worsening
No
improvement
Lytic changes
Decreasing
trabeculation
Increased size
of radiographic
lesion
