ASCO GUIDELINES Bundle

Medication-Related Osteonecrosis of the Jaw

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11 MRONJ Management Flow Diagram Oncologist Dentist Dental Specialist 6-month preventative follow-up 8-week management follow-up Oncologist Dentist • Consider continuation vs. discontinuation of BMA therapy in patients newly diagnosed with MRONJ • Inform patient of required dental assessments and need for commitment to oral care • Refer patient to own family dentist or a dentist that is identified as liaison to cancer program • Reinforce modifiable risk factors: invasive dental procedure, diabetes, periodontal disease, denture use, smoking • Provide the dentist with the patients' medical diagnosis, antiresorptive and angiogenic inhibitor profile • Indicate if patient has already commenced therapy and duration Oncologist Dentist • Send dental diagnosis and treatment plan to oncologist • Coordinate with oncologist if oral surgery is necessary • Identify any modifiable risk factors: invasive dental procedure, diabetes, periodontal disease, denture use, smoking

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