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Disclaimer
is pocket guide is derived om recommendations in the American Society of Clinical
Oncology Guideline. is resource is a practice tool based on ASCO
®
practice guidelines and is
not intended to substitute for the independent professional judgment of the treating physician.
Practice guidelines do not account for individual variation among patients. is pocket guide
does not purport to suggest any particular course of medical treatment. Use of the practice
guidelines and this resource are voluntary. e practice guidelines and additional information
are available at www.asco.org/head-neck-cancer-guidelines. Copyright © 2019 by American
Society of Clinical Oncology. All rights reserved.
Source
Koyfman SA, Ismaila N, Crook D, D'Cruz A, Rodriguez CP, Sher DJ, Silbermins D, Sturgis
EM, Tsue T, Weiss J, Yom SS and Holsinger FC. Management of the Neck in Squamous Cell
Carcinoma of the Oral Cavity and Oropharynx: ASCO Clinical Practice Guideline. J Clin
Oncol. 2019 Feb 27 doi 10.1200/JCO.18.01921
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ASCO believes that cancer clinical trials are vital to inform medical decisions and
improve cancer care and that all patients should have the opportunity to participate.
Additional information, which may include data supplements, slide sets, and other clinical
tools and resources, is available at www.asco.org/head-neck-cancer-guidelines
Abbreviations
ASCO, American Society of Clinical Oncology; CT, computed tomography; END,
elective neck dissection; FDG, fludeoxyglucose; HNC, Head and neck cancer; HPV,
human papillomavirus; MRI, magnetic resonance imaging ; cN0, clinically node negative;
cN+, clinically node-positive; PET/CT, positron emission tomography and computed
tomography; pN0, pathologically node negative; pN+, pathologically node positive; RT,
radiotherapy SCC, squamous cell carcinoma; SCCOC, squamous cell carcinoma of oral
cavity; SCCOP, squamous cell carcinoma of the oropharynx; Gy, Gray
Recommendation Grading
Type Benefit/harm Evidence Quality
Strength of
Recommendation
EB Evidence-
based
B Benefits
outweigh harms
H High Strong
FC
Formal
consensus
H Harms outweigh
benefits
I Intermediate Moderate
IC Informal
consensus
B/H Relative balance
of benefits and
harms
L Low Weak
Ins Insufficient
