ASCO GUIDELINES Bundle

Fertility Preservation in Cancer Patients

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Key Points Recommendation 1.1 ➤ People with cancer are interested in discussing fertility preservation. Health care providers caring for adult and pediatric patients with cancer (including medical oncologists, radiation oncologists, gynecologic oncologists, urologists, hematologists, pediatric oncologists, surgeons, and others) should address the possibility of infertility as early as possible before treatment starts. Recommendation 1.2 ➤ Health care providers should refer patients who express an interest in fertility preservation (and those who are ambivalent) to reproductive specialists. Recommendation 1.3 ➤ To preserve the full range of options, fertility preservation approaches should be discussed as early as possible, before treatment starts. The discussion can ultimately reduce distress and improve quality of life. Another discussion and/or referral may be necessary when the patient returns for follow-up after completion of therapy and/or if pregnancy is being considered. The discussions should be documented in the medical record. Adult Men Recommendation 2.1 ➤ Sperm cryopreservation: Sperm cryopreservation is effective, and health care providers should discuss sperm banking with postpubertal males receiving cancer treatment. Recommendation 2.2 ➤ Hormonal gonadoprotection: Hormonal therapy in men is not successful in preserving fertility. It is NOT recommended. ➤ The goal of this 2018 pocket guide update is to provide current guidance regarding fertility preservation options for people with cancer anticipating treatment. Treatment

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