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Bone-Modifying Agents in Multiple Myeloma

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106 Commerce Street, Suite 105 Lake Mary, FL 32746 TEL: 407.878.7606 • FAX: 407.878.7611 Order additional copies at GuidelineCentral.com Copyright © 2018 All rights reserved Disclaimer is pocket card is derived om recommendations in the American Society of Clinical Oncolog y Guideline. is resource is a practice tool based on ASCO ® practice guidelines and is not intended to substitute for the independent professional judgment of the treating physician. Practice guidelines do not account for individual variation among patients. is pocket card does not purport to suggest any particular course of medical treatment. Use of the practice guidelines and this resource are voluntary. e practice guidelines and additional information are available at www.asco.org/ hematologic-malignancies-guidelines. Copyright © 2018 by American Society of Clinical Oncolog y. All rights reserved. ASCOBMAMM17123a Abbreviations BMA, bone-modifying agents; CRAB, hypercalcemia, renal dysfunction, anemia or bone disease; CT, computed tomography; FDA, U.S. Food and Drug Administration; mg, milligram(s); MRI, magnetic resonance imaging ; ONJ, osteonecrosis of the jaw; PET, positron emission tomography; USD, United States dollars Source Anderson K, Ismaila N, Flynn PJ, Halabi S, Jagannath S, Ogaily MS, Omel J, Raje N, Roodman GD, Yee GC, Kyle RA. Role of Bone-Modifying Agents in Multiple Myeloma: American Society of Clinical Oncolog y Clinical Practice Guideline Update. J Clin Oncol. 2018 Jan 17. doi: 10.1200/JCO.2017.76.6402 ASCO believes that cancer clinical trials are vital to inform medical decisions and improve cancer care and that all patients should have the opportunity to participate. Additional information, which may include data supplements, slide sets, frequently asked questions, and other clinical tools and resources, is available at www.asco.org/hematologic-malignancies-guidelines and www.asco.org/guidelineswiki

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