11
Oncotype DX
MammaPrint
a
EndoPredict
ProSigna
Ki67
b
IHC4
b
BCI
c
uPA and PAI-1
d
Oncotype DX
MammaPrint
a
Ki67
b
EndoPredict
IHC4
b
BCI
c
Insufficient
evidence to
recommend a
biomarker for use
No mature evidence to
recommend use of any
other biomarker for this
patient population
Node–
1–3
Node+
Postmenopausal
or age >50 years
>3
Node+
High quality of evidence/Strong strength of recommendation.
Intermediate quality of evidence/Strong strength of recommendation.
Intermediate quality of evidence/Moderate strength of recommendation.
ER–
Node+
