7
Growing data shows
cognitive impairment
is associated with
poorer survival in older
patients with cancer and
increased chemotherapy
toxicity risk.
Mini-Cog has been
shown to have high
sensitivity and specificity
for identifying cognitive
impairment when
compared to longer tools.
BOMC is practical and is
included in the Cancer-
Specific GA developed
by Hurria et al.
Administered; ≤5 min Multiple tools are available for
cognitive assessment.
e Mini Mental State
Examination (MMSE)
has more robust data for
prediction of outcomes in
older patients with cancer and
has been shown to predict
chemotherapy toxicity; it is
included in the CRASH tool
developed by Extermann et al.
e Montreal Cognitive
Assessment (MOCA) is also
utilized by geriatricians.
Both MMSE and MOCA
are considerably longer than
Mini-Cog and BOMC.
Depression has
been associated
with unexpected
hospitalizations,
treatment tolerance,
mortality, and functional
decline in older adults
with cancer receiving
chemotherapy; these
studies primarily assessed
depression with the
GDS.
PRO; ≤5 min GDS recommended also
by ASCO guidelines for
depression.
e Patient Health
Questionnaire-9 is an
alternative and is also
recommended by ASCO
guidelines for depression.
e Mental Health Inventory
is an option and has been
associated with outcomes
in older patients with breast
cancer.
Poor nutrition is
associated with mortality
in older patients with
cancer.
PRO; <1 min Consider G8 and Mini-
Nutritional Assessment
(MNA) as alternatives; both
are associated with mortality
in older patients with cancer.
