5
Evidence to Support
Recommendation
Administration
Characteristics
Considerations and other
evaluation options
Large prospective studies
of older patients with
cancer show IADLs
predict chemotherapy
toxicity, mortality,
hospitalizations, and
functional decline.
Advocated by experts in
Delphi consensus panels.
Patient reported outcome
(PRO); <5 min
Consider ADLs; Any
ADL deficit is utilized for
characterization of frailty
Consider objective measure
of physical performance
such as Short Physical
Performance Battery (SPPB);
Timed Up and Go (TUG);
or Gait Speed
Falls are common in
older adults with cancer
and can lead to serious
injury.
Falls have been associated
with chemotherapy
toxicity.
Assessment for falls
is recommended by
geriatric oncolog y expert
panels and the American
Geriatrics Society for all
older adults
PRO;<1 min
Comorbidity is
associated with poorer
survival, chemotherapy
toxicity, mortality, and
hospitalizations.
Part of routine history Consider validated tools
such as CIRS-G or Charlson;
history, CIRS-G, OARS
comorbidity recommended
by experts
