10
Figures
Volume of gas containing CO
measured by the dilution of an inert
tracer gas in the inspired volume (V
A
)
Measured carbon
monoxide concentration
change over time (K
CO
)
• Incomplete lung expansion
▶ e.g., failure to take deep
breath, neuromuscular
dysfunction
• Localized loss of lung
volume
▶ e.g., pneumonectomy
• Loss of alveoli capillary
structure with loss of
lung volume
▶ e.g., emphysema,
interstitial lung
disease (ILD)
Figure 6. Approach to Interpretation of D
L
CO
