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Arteritis ACR 2021

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8 Treatment/Management of GCA Figure 1. Key Recommendations for the Treatment of GCA Active GCA High-dose IV pulse GC followed by high-dose daily oral GC with TCZ over GC alone; In some instances, can consider GC with MTX or GC alone Consider adding or changing non-GC immunosuppressive agent (e.g., MTX or ABA instead of TCZ) Taper daily oral GC Visual symptoms/loss or critical cranial ischemia Treatment option, Conditional recommendation Treatment option, Strong recommendation Disease status decision point Assessed disease status Clinical remission NO YES

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