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Coronary Artery Revascularization

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35 Table 9. Perioperative Anesthetic and Monitoring Considerations for CABG Anesthetic considerations Perioperative analgesia Nonopioid medications (e.g., acetaminophen, ketamine, dexmedetomidine) and/or regional techniques (e.g., truncal nerve blocks), particularly as part of a multimodal analgesic approach, have been shown to reduce perioperative opioid use in cardiac surgery. Maintenance anesthesia Although volatile (versus intravenous) anesthesia may facilitate earlier extubation, recent evidence suggests that the choice of maintenance anesthetic likely does not impact mortality rate after cardiac surgery. Mechanical ventilation An intraoperative lung-protective ventilation strategy (i.e., tidal volume of 6–8 mL/kg predicted body weight + positive end-expiratory pressure) has been shown to improve pulmonary mechanics and reduce postoperative pulmonary complications. Goal-directed therapy Goal-directed therapy, which creates protocols for the use of fluids and vasopressors to target specific hemodynamic goals, has yielded inconsistent results and requires additional investigation to determine its use in cardiac surgery. TEE CABG + valve procedures Intraoperative TEE aids in the real-time assessment of heart valve function and pathology in those undergoing combination CABG and valve surgery. Isolated CABG procedures The use of intraoperative TEE in isolated CABG is less established but has been shown to aid in surgical and anesthetic decision-making as a tool for real-time assessment of hemodynamic status, regional wall motion, ventricular function, valve anatomy, and diastolic function. Perioperative Considerations in Patients Undergoing CABG COR LOE Recommendation 1 B-NR 1. For patients undergoing CABG, establishment of multidisciplinary, evidence-based perioperative management programs is recommended to optimize analgesia, minimize opioid exposure, prevent complications and to reduce time to extubation, length of stay, and healthcare costs. General Procedural Issues for CABG

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