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2021 Chest Pain Guidelines

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50 Treatment 5.2.1.1. Patients With Prior Coronary Artery Bypass Surgery With Stable Chest Pain COR LOE Recommendations 1 C-LD 1. In patients who have had prior coronary artery bypass surgery presenting with stable chest pain whose noninvasive stress test results show moderate to severe ischemia, or in those suspected to have myocardial ischemia with indeterminate/ nondiagnostic stress test, ICA is recommended for guiding therapeutic decision-making. 2a C-LD 2. In patients who have had prior coronary artery bypass surgery presenting with stable chest pain who are suspected to have myocardial ischemia, it is reasonable to perform stress imaging or CCTA to evaluate for myocardial ischemia or graft stenosis or occlusion. 5.2.2. Patients With Known Nonobstructive CAD Presenting With Stable Chest Pain COR LOE Recommendations Index Diagnostic Testing: Selecting the Appropriate Test Anatomic Testing 2a B-NR 1. For symptomatic patients with known nonobstructive CAD who have stable chest pain, CCTA is reasonable for determining atherosclerotic plaque burden and progression to obstructive CAD, and guiding therapeutic decision-making. 2a B-NR 2. For patients with known coronary stenosis from 40% to 90% on CCTA, FFR can be useful for diagnosis of vessel-specific ischemia and to guide decision-making regarding the use of ICA. Stress Testing 2a C-LD 3. For patients with known extensive nonobstructive CAD with stable chest pain symptoms, stress imaging (PET/SPECT, CMR, or echocardiography) is reasonable for the diagnosis of myocardial ischemia.

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