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2021 Chest Pain Guidelines

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43 5.1.3. Intermediate-High Risk Patients With Stable Chest Pain and No Known CAD COR LOE Recommendations Secondary Diagnostic Testing: What to Do If Index Test Results Are Positive or Inconclusive Sequential or Add-on Testing 2a B-NR 7. For intermediate-high risk patients with stable chest pain and known coronary stenosis of 40% to 90% in a proximal or middle coronary segment on CCTA, FFR-CT can be useful for diagnosis of vessel-specific ischemia and to guide decision- making regarding the use of coronary revascularization. 2a B-NR 8. For intermediate-high risk patients with stable chest pain after an inconclusive or abnormal exercise ECG or stress imaging study, CCTA is reasonable. 2a B-NR 9. For intermediate-high risk patients with stable chest pain and no known CAD undergoing stress testing, the addition of CAC testing can be useful. 2a B-NR 10. For intermediate-high risk patients with stable chest pain after inconclusive CCTA, stress imaging is reasonable. 2b C-EO 11. For intermediate-high risk patients with stable chest pain after a negative stress test but with high clinical suspicion of CAD, CCTA or ICA may be reasonable. (cont'd)

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