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2021 Chest Pain Guidelines

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33 Stress testing: Stress CMR Stress echocardiography Stress PET Stress SPECT (2a) Discharge Option to defer ICA with mildly abnormal test Obstructive CAD ‡ (≥50% stenosis) High-risk CAD § or frequent angina Abnormal functional test Normal functional test Test choice should be guided by local availability and expertise. * Known CAD is prior MI, revascularization, known obstructive or nonobstructive CAD on invasive or CCTA. † If extensive plaque is present a high-quality CCTA is unlikely to be achieved, and stress testing is preferred ‡ Obstructive CAD includes prior coronary artery bypass gra/percutaneous coronary intervention. § High-risk CAD means le main stenosis ≥ 50%; anatomically significant 3-vessel disease (≥70% stenosis). ║ FFR-CT turnaround times may impact prompt clinical care decisions.

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