23
Table 4. Recommended Initial Laboratory Screening and
Other Studies in Persons with HIV
Test Comment(s)
Tests at May Be Performed Under Certain Circumstances (cont'd)
Pregnancy test in persons of child-
bearing potential
Pregnancy status is required to inform choice
of ART and in discussions about conception in
persons of child-bearing potential.
Serum testosterone level In cisgender males with fatigue, weight loss, loss of
libido, erectile dysfunction, or depression or who
have evidence of reduced bone mineral density.
Morning free testosterone preferred. See Section
IV for management of hypogonadism.
Tests at Are
NOT Recommended for General Screening Purposes
HSV IgG, CMV IgG, Toxoplasma
IgG, biomarkers of inflammation.
In asymptomatic persons, routine testing for all
persons is NOT recommended for HSV, CMV,
and
Toxoplasma. Biomarkers of inflammation
are NOT recommended. Toxoplasma IgG and
cryptococcal antigen should be obtained in
the context of suspicion for clinical disease.
Toxoplasma IgG may be obtained in patients for
whom prophylaxis is indicated. CMV IgG may be
considered if blood transfusion is contemplated in
a person at low risk for CMV exposure. A negative
CMV IgG may support use of CMV-free blood
products.
Serum cryptococcal antigen in
persons with CD4 ≥100/mm
3
.
Serum cryptococcal antigen may be considered for
persons with CD4 <100/mm
3
.
(cont'd)
