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Primary Care Guidance for Persons With HIV - 2021

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23 Table 4. Recommended Initial Laboratory Screening and Other Studies in Persons with HIV Test Comment(s) Tests at May Be Performed Under Certain Circumstances (cont'd) Pregnancy test in persons of child- bearing potential Pregnancy status is required to inform choice of ART and in discussions about conception in persons of child-bearing potential. Serum testosterone level In cisgender males with fatigue, weight loss, loss of libido, erectile dysfunction, or depression or who have evidence of reduced bone mineral density. Morning free testosterone preferred. See Section IV for management of hypogonadism. Tests at Are NOT Recommended for General Screening Purposes HSV IgG, CMV IgG, Toxoplasma IgG, biomarkers of inflammation. In asymptomatic persons, routine testing for all persons is NOT recommended for HSV, CMV, and Toxoplasma. Biomarkers of inflammation are NOT recommended. Toxoplasma IgG and cryptococcal antigen should be obtained in the context of suspicion for clinical disease. Toxoplasma IgG may be obtained in patients for whom prophylaxis is indicated. CMV IgG may be considered if blood transfusion is contemplated in a person at low risk for CMV exposure. A negative CMV IgG may support use of CMV-free blood products. Serum cryptococcal antigen in persons with CD4 ≥100/mm 3 . Serum cryptococcal antigen may be considered for persons with CD4 <100/mm 3 . (cont'd)

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