Other Conditions
14
➤ 7.3 In adults with cured Cushing syndrome, we advise the approach to CV
risk assessment and treatment be the same as in the general population.
(UGPS)
Lipid Management in Chronic Glucocorticoid Therapy
➤ 7.4 In adults receiving chronic glucocorticoid therapy above replacement
levels, we suggest assessment and treatment of lipids and other CV risk
factors because of the increased risk of CVD. (2|⊕
)
Technical Remark:
▶ Effects of glucocorticoid therapy on lipids and CV risk will vary based on dose of
glucocorticoid, duration of treatment, and underlying disease/indication.
8. Disorders Of Growth Hormone Secretion
Adult Growth Hormone Deficiency
➤ 8.1 In adults with GHD, we recommend obtaining a lipid profile at
diagnosis to assess for dyslipidemia. (1|⊕⊕⊕
)
➤ 8.2 In adults with GHD associated with hypopituitarism, we suggest
assessment and treatment of lipids and other CV risk factors. (2|⊕
)
Technical Remarks:
▶ LDL-C should be the primary target.
▶ Consider therapy if LDL-C is over 70 mg/dL (1.8 mmol/L).
➤ 8.3 In adult patients with GHD, we recommend against using growth
hormone replacement solely to lower LDL-C to reduce CV risk. (1|⊕⊕⊕
)
Growth Hormone Excess (Acromegaly)
➤ 8.4 In adults with acromegaly, we suggest measurement of the usual lipid
profile before and after treatment of growth hormone excess. (2|⊕
)
