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Lipid Management in Endocrine Disorders

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Obesity 12 ➤ 5.4 In individuals who have obesity and are on pharmacological therapy for weight reduction, we suggest reassessment of the lipid profile to evaluate the risk of CVD and pancreatitis. (2|⊕ ) Technical Remark: ▶ As there are no data on the timing of lipid measurements after weight loss, we suggest reassessment of lipids after 5% weight loss and periodically thereafter and when the weight is stable. ➤ 5.5 In individuals with obesity, (body mass index >40 or >35 kg/m 2 with comorbidities) who undergo bariatric surgery, we suggest measurement of the lipid profile after bariatric surgery to assess CV risk. (2|⊕ ) Technical Remarks: ▶ Malabsorptive bariatric surgery procedures (e.g., Roux-en-Y gastric bypass) are more effective than restrictive procedures (e.g., banding, sleeve gastrectomy) in decreasing LDL-C levels. ▶ Both restrictive and malabsorptive procedures decrease TG. ▶ Reassess lipid profile 1 to 3 months after bariatric surgery and periodically thereafter and when the weight is stable.

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