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Obesity-Related Diseases - Obesity Algorithm 2024

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Abbreviations ALT, alanine transaminase; AT, adipose tissue; BNP, B-type natriuretic peptide; CETP, cholesteryl ester transfer protein; CVD, cardiovascular disease; CVOT, cardiovascular outcome trial; EAT, epicardial adipose tissue; FFA, f ree fatty acids; FIB-4, Fibrosis 4 Index Panel; GIP, glucose- dependent insulinotropic polypeptide; GLP-1 RA, glucagon-like peptide-1 receptor agonist; GLUT, glucose transporter; HFpEF, heart failure with preserved ejection f raction; HDL, high density lipoprotein; HDL-C, high density lipoprotein cholesterol; HSL, hormone sensitive lipase; LDL, low density lipoprotein; LPL, lipoprotein lipase; MACE, major adverse cardiovascular events; MASLD, metabolic dysfunction- associated steatotic liver disease; MASH, metabolic dysfunction associated steatohepatitis; PCOS, polycystic ovary syndrome; RAAS, renin-angiotensin aldosterone system; ROS, reactive oxygen species; SELECT, semaglutide in patients with obesity; SGLT, sodium glucose transporter; SOUL, semaglutide in patients with type 2 diabetes; T2DM, type 2 diabetes mellitus; TGs, triglycerides; VCTE, vibration-controlled elastography; VLDL, very low-density lipoproteins; WHO, World Health Organization Source Tondt J, Freshwater M, Benson-Davies S, Dawkins C, Magee J, Karjoo S, Ortiz Page, SO, Pile H, Khan N, Hurtado Andrade M, Rajpal A, Petcu A, Antoun J, Haq H, Fryoux E, Gugnani, K, Manek M, Aranas MP, Afreen S. Obesity Algorithm eBook, presented by the Obesity Medicine Association. www.obesityalgorithm.org. 2024. https://obesitymedicine.org/resources/ obesity-algorithm/(Accessed = February 2024) 1258 Upsala Rd Sanford, FL 32771 TEL: 407.878.7606 FAX: 407.878.7611 Copyright © 2024 All rights reserved Obesity Medicine Association 7173 S. Havana St #600–130 Centennial, CO 80112 TEL: 303.770.2526 OMAOBEAD03242a Disclaimer is resource is for informational purposes only, intended as a quick-reference tool based on the cited source guideline(s), and should not be used as a substitute for the independent professional judgment of healthcare providers. Practice guidelines are unable to account for every individual variation among patients or take the place of clinician judgment, and the ultimate decision concerning the propriety of any course of conduct must be made by healthcare providers aer consideration of each individual patient situation. Guideline Central does not endorse any specific guideline(s) or guideline recommendations and has not independently verified the accuracy hereof. Any use of this resource or any other Guideline Central resources is strictly voluntary.

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