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Chronic Disease of Obesity - Obesity Algorithm 2024

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29   ➤ Screening: • Screen for Disordered Eating (SDE), Eating Disorders Screen for Primary Care (EDSPC), Eating Disorder Inventory (EDI) and EAT. • Sick (vomiting), Control (loss of control), One Stone (loss of ~15 pounds in 3 months), Fat (disturbance in body fat image), Food (obsession with eating behavior) = SCOFF.   ➤ Treatment: • Cognitive behavior therapy and avoidance of restrictive eating patterns, possibly in combination with drug treatment. • Fluoxetine is an FDA-approved pharmacotherapy for bulimia nervosa. • Although not FDA-indicated for this use, topiramate and naltrexone may be eff icacious in treating bulimia nervosa. NES   ➤ Diagnosis: • At least 25% of daily food consumption (often greater than 50%) consumed after evening meal. • Recurrent awakenings f rom sleep that require eating to go back to sleep, often involving carbohydrate-rich snacks. • Little interest in breakfast (morning anorexia). • NES may occur in as much as 1.5% of the U.S. population. • Awareness of evening or nocturnal ingestions help differentiate NES f rom SRED.   ➤ Treatment: • Behavioral therapy regarding nutritional timing and content. • While not an indicated use, selective serotonin re-uptake inhibitors (e.g., sertraline) or anti-migraine/seizure topiramate may be useful for NES. Sleep-Related Eating Disorder   ➤ SRED is a parasomnia (undesired events accompanying sleep) with "sleep-walking" resulting in repeated episodes of compulsive binge eating and drinking after waking up at night. • SRED usually occurs while partially awake and often with no memory of the event afterward.

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