21
Some Drug Interactions Contraindications
• Monoamine oxidase inhibitors:
phentermine is contraindicated
during or within 14 days following
the administration of these
medications because of the risk of
hypertensive crisis.
• Alcohol: concomitant use of
alcohol with phentermine may
result in an adverse drug reaction.
• Insulin and oral hypoglycemic
medications: concomitant
use of these medications
and phentremine may cause
hypoglycemia. A reduction in
insulin or oral hypoglycemic
medications in people with
diabetes mellitus may be required.
• Adrenergic Neuron Blocking
Drugs: Phentermine may
decrease the hypotensive effect
of adrenergic neuron blocking
drugs.
• Hypersensitivity
• Pregnancy/nursing
• History of cardiovascular
disease (e.g., coronary artery
disease, stroke, arrhythmias,
congestive heart failure,
uncontrolled hypertension)
• Administration during or
within 14 days following the
administration of monoamine
oxidase inhibitors
• Uncontrolled hyperthyroidism
• Glaucoma
• Agitated states
• History of drug abuse
• Concomitant SSRI
