8
Diagnosis
Table 1. Sources of Antigens Known to Cause HP
Matter Typical Sources HP "Disease"
Inorganic Particulate Matter
I. Chemicals
Acid anhydrides
(pyromellitic and trimellitic
anhydrides)
Polyurethane foams, spray
paints, elastomers, glues,
adhesives, mattresses, car parts,
shoes, imitation leather, rubber
products, chipboards, elastic
synthetic fibers, electrical
insulations
Acid anhydride
alveolitis
Acrylate compounds (methyl
methacrylate)
Dental materials, lacquer, resin,
glues
Methacrylate
alveolitis
Copper sulfate Copper-sulfate Bordeaux
mixture
Vineyard sprayer's
lung
Chloroethylene
(trichlorethylene)
Degreasing agents, cleaning
agents, extraction agents
Chemical alveolitis
Dimethyl phthalate and
styrene
Industrial solvents, plasticizers —
HFC-134a Coolant fluid in laser hair-
removal devices
Hair-remover lung
Isocyanates (toluene
diisocyanate, methylene
diphenyl diisocyanate,
hexamethylene diisocyanate,
MIC, NDI, polyisocyanate)
As in acid anhydrides Isocyanate alveolitis
Tetrachlorophthalic and
hexahydrophthalic acid
Hardener for epoxy resin Acid anhydride
alveolitis
Sodium diazobenzene sulfate Laboratory reagent,
chromatography
Chemical alveolitis
Triglycidyl isocyanurate Polyester powder (powder
paints)
Painter's lung
II. Pharmaceutical Agents
Penicillins, cephalosporins Antibiotics Drug-induced HP
Methotrexate Immunosuppressive agents
α-IFN Immunomodulatory agents
Lenalidomide Hypolipidemics
Pravastatin Antidepressants
Venlafaxine Alkylating agents
Temozolomide
(cont'd)
