ATS GUIDELINES Bundle

Hypersensitivity Pneumonitis in Adults

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11 Table 3. Radiological Terms for Heterogenous Lung Attenuation Terminology Significance Description "ree-density pattern" a • Term coined to replace the "headcheese" sign, since most individuals worldwide do not relate to the headcheese sign • Combination of three attenuations on inspiratory CT images: a. Normal-appearing lung b. High attenuation (GGO) c. Lucent lung (i.e., regions of decreased attenuation and decreased vascular sections) • Indicative of a mixed obstructive and infiltrative process: a. The obstructive abnormality (seen in small airway disease) is manifested by areas of decreased attenuation and decreased vascularity. b. The infiltrative disorder results in GGO surrounding preserved normal lobules. • Sharply demarcated from each other • Highly specific for fibrotic HP; has not been shown to be specific for nonfibrotic HP a e term "three-density pattern" was coined by this committee. is descriptive pattern was unanimously determined by the committee to be the preferred term. is pattern has been shown to differentiate fibrotic HP from idiopathic pulmonary fibrosis and, thus, raises the index of suspicion for the diagnosis of fibrotic HP whenever present. However, it is unknown whether the pattern is also present in nonfibrotic HP. Some radiologists relate this pattern to the appearance of headcheese and, therefore, it has been referred to as the "headcheese sign" in the literature. e guideline committee strongly discourages the use of the term "headcheese" to describe this pattern. (cont'd)

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