Document Assessment
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Figure 11
Evolution of aortic dissection flap morpholog y over time demonstrating transition from acute to
subacute to chronic dissection.
Table IV. Acute Kidney Injury Network (AKIN) classification/
staging system for acute kidney injury
a
Stage Serum creatinine criteria Urine output criteria
1 Increase in serum creatinine of ≥0.3 mg/dL
(≥26.4 mmol/L) or increase to ≥150% to
200% (1.5- to 2-fold) from baseline
<0.5 mL/kg per hour for >6
hours
2b Increase in serum creatinine to >200% to
300% (>2- to 3-fold) from baseline
<0.5 mL/kg per hour for >12
hours
3c Increase in serum creatinine to >300%
(>3-fold) from baseline (or serum
creatinine of ≥4.0 mg/dL [≥354 mmol/L]
with an acute increase of at least 0.5 mg/dL
[44 μmol/L])
<0.3 mL/kg per hour for 24
hours or anuria for 12 hours
a
Modified from RIFLE (Risk, Injury, Failure, Loss, and End-stage kidney disease) criteria. American
Society of Nephrolog y Renal Research Report. J Am Soc Nephrol 2005;16:1886-1903.
b
A 200%–300% increase equals a twofold to threefold increase.
c
Given wide variation in indications and timing of initiation of renal replacement therapy (RRT),
individuals who receive RRT are considered to have met the criteria for stage 3 irrespective of the
stage they are in at the time of RRT.
From: Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, et al. Acute Kidney
Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care
2007;11:R31.
