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Chronic Limb-Threatening Ischemia

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Treatment 22 Summary of Recommendations Recommendation Grade/ LOE 9.6 Involve a multidisciplinary rehabilitation team from the time a decision to amputate has been made until successful completion of rehabilitation has been achieved. 1-C 9.7 Continue to observe CLTI patients who have undergone amputation at least yearly to monitor progression of disease in the contralateral limb and to maintain optimal medical therapy and risk factor management. 1-C 10. Postprocedural care and surveillance aer infrainguinal revascularization for CLTI 10.1 Continue best medical therapy for PAD, including the long-term use of antiplatelet and statin therapies, in all patients who have undergone lower extremity revascularization. 1-A 10.2 Promote smoking cessation in all CLTI patients who have undergone lower extremity revascularization. 1-A 10.3 Consider DAPT (aspirin plus clopidogrel) in patients who have undergone infrainguinal prosthetic bypass for CLTI for a period of 6–24 months to maintain gra patency. 2-B 10.4 Consider DAPT (aspirin plus clopidogrel) in patients who have undergone infrainguinal endovascular interventions for CLTI for ≥1 month. 2-C 10.5 Consider DAPT for 1–6 months in patients undergoing repeated catheter-based interventions if they are at low risk for bleeding. 2-C 10.6 Observe patients who have undergone lower extremity vein bypass for CLTI on a regular basis for ≥2 years with a clinical surveillance program consisting of interval history, pulse examination, and measurement of resting APs and TPs. Consider DUS scanning where available. GPS 10.7 Observe patients who have undergone lower extremity prosthetic bypass for CLTI on a regular basis for ≥2 years with interval history, pulse examination, and measurement of resting APs and TPs. GPS 10.8 Observe patients who have undergone infrainguinal endovascular interventions for CLTI in a surveillance program that includes clinical visits, pulse examination, and noninvasive testing (resting APs and TPs). GPS 10.9 Consider performing additional imaging in patients with lower extremity vein gras who have a decrease in ABI ≥0.15 and recurrence of symptoms or change in pulse status to detect vein gra stenosis. GPS

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