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Chronic Limb-Threatening Ischemia

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Diagnosis 6 Table 1. Wound grading in Wound, Ischemia, and foot Infection (WIfI) classification Grade Ulcer Gangrene 0 No ulcer No gangrene Clinical description: ischemic rest pain (requires typical symptoms + ischemia grade 3); no wound. 1 Small, shallow ulcer on distal leg or foot; no exposed bone, unless limited to distal phalanx No gangrene Clinical description: minor tissue loss. Salvageable with simple digital amputation (1 or 2 digits) or skin coverage. 2 Deeper ulcer with exposed bone, joint, or tendon; generally not involving the heel; shallow heel ulcer, without calcaneal involvement Gangrenous changes limited to digits Clinical description: major tissue loss salvageable with multiple (≥3) digital amputations or standard TMA ± skin coverage. 3 Extensive, deep ulcer involving forefoot and/or midfoot; deep, full-thickness heel ulcer ± calcaneal involvement Extensive gangrene involving forefoot and/or midfoot; full- thickness heel necrosis ± calcaneal involvement Clinical description: extensive tissue loss salvageable only with a complex foot reconstruction (nontraditional transmetatarsal, Chopart, or Lisfranc amputation); flap coverage or complex wound management needed for large, so tissue defect. Table 2. Ischemia grading in Wound, Ischemia, and foot Infection (WIfI) classification Grade ABI Ankle systolic pressure TP, TcPO2 0 ≥0.80 >100 mm Hg ≥60 mm Hg 1 0.6-0.79 70-100 mm Hg 40-59 mm Hg 2 0.4-0.59 50-70 mm Hg 30-39 mm Hg 3 ≤0.39 <50 mm Hg <30 mm Hg

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