29
Diphenhydramine
Benadryl
Trihexyphenidyl hydrochloride
Artane
No dose adjustments noted in
labeling. However, dosing interval
may need to be increased or dosage
reduced in older individuals and
those with renal impairments.
No dose adjustments noted in
labeling
Total daily dose typically divided into
3–4 doses per day.
Maximum daily dose 300 mg for oral
and 400 mg for IM/IV, with 100 mg
maximum dose for IV/IM.
Give IV dose at a rate of 25 mg/minute.
Give IM dose by deep intramuscular
injection because subcutaneous
or intradermal injection can cause
local necrosis.
