12
Treatment
Table 6. Common Adverse Drug Reactions and Monitoring
Recommendations
a
Drug Adverse Reactions Monitoring
Azithromycin/
clarithromycin
Gastrointestinal Clinical monitoring
Tinnitus/hearing loss Audiogram
Hepatotoxicity Liver function tests
Prolonged QTc ECG (QTc)
Clofazimine Tanning of skin and dryness Clinical monitoring
Hepatotoxicity Liver function tests
Prolonged QTc ECG (QTc)
Doxycycline GI upset Clinical monitoring
Photosensitivity Clinical monitoring
Tinnitus/vertigo Clinical monitoring
Ethambutol Ocular toxicity Visual acuity and color
discrimination
Neuropathy Clinical monitoring
Isoniazid Hepatitis Liver function tests
Peripheral neuropathy Clinical monitoring
Linezolid Peripheral neuropathy Clinical monitoring
Optic neuritis Visual acuity and color
discrimination
Cytopenias Complete blood count
Moxifloxacin Prolonged QTc ECG (QTc)
Hepatotoxicity Liver function tests
Tendinopathy Clinical monitoring
Trimethoprim/
sulfamethoxazole
GI upset Clinical monitoring
Cytopenias Complete blood count
Hypersensitivity Clinical monitoring
Photosensitivity Clinical monitoring
Rifabutin Uveitis Visual acuity
